The Myc-dependent angiogenic switch in tumors is mediated by interleukin 1β

Although induction of blood vessel growth is acknowledged as a pivotal requirement for the evolution of macroscopic tumors, the events that trigger onset of tumor angiogenesis remain largely obscure. The pervasive Myc oncoprotein is itself a potent inducer of angiogenesis in a wide range of tissues....

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Bibliographic Details
Main Authors: Shchors, Ksenya, Shchors, Elena, Rostker, Fanya, Lawlor, Elizabeth R., Brown-Swigart, Lamorna, Evan, Gerard I.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2006
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1578676/
https://ncbi.nlm.nih.gov/pubmed/16980582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1455706
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