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Acute Overexpression of Myc in Intestinal Epithelium Recapitulates Some but Not All the Changes Elicited by Wnt/β-Catenin Pathway Activation

The Myc transcription factor is a potent inducer of proliferation and is required for Wnt/β-catenin signaling in intestinal epithelium. Since deregulation of the Wnt/β-catenin pathway is a prerequisite for nonhereditary intestinal tumorigenesis, we asked whether activation of Myc recapitulates the t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Finch, Andrew J., Soucek, Laura, Junttila, Melissa R., Swigart, Lamorna Brown, Evan, Gerard I.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747972/
https://ncbi.nlm.nih.gov/pubmed/19635809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01745-08
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