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Distinct thresholds govern Myc’s biological output in vivo
Deregulated Myc triggers a variety of intrinsic tumor suppressor programs that serve to restrain Myc’s oncogenic potential. Since Myc activity is also required for normal cell proliferation, activation of intrinsic tumor suppression must be triggered only when Myc signaling is oncogenic. However, ho...
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| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2723751/ https://ncbi.nlm.nih.gov/pubmed/19061836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2008.10.018 |
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