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Cyclin D1 is frequently overexpressed in microsatellite unstable colorectal cancer, independent of CpG island methylator phenotype

AIMS: Cyclin D1 and cyclin-dependent kinases are commonly activated in colorectal cancer. Microsatellite instability (MSI) and CpG island methylator phenotype (CIMP) are important molecular classifiers in colorectal cancer. However, the relationship between cyclin D1, MSI and CIMP has been uncertain...

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Hlavní autoři: Nosho, Katsuhiko, Kawasaki, Takako, Chan, Andrew T., Ohnishi, Mutsuko, Suemoto, Yuko, Kirkner, Gregory J., Fuchs, Charles S., Ogino, Shuji
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719983/
https://ncbi.nlm.nih.gov/pubmed/18983468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2559.2008.03161.x
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