Cyclin D1 is frequently overexpressed in microsatellite unstable colorectal cancer, independent of CpG island methylator phenotype

AIMS: Cyclin D1 and cyclin-dependent kinases are commonly activated in colorectal cancer. Microsatellite instability (MSI) and CpG island methylator phenotype (CIMP) are important molecular classifiers in colorectal cancer. However, the relationship between cyclin D1, MSI and CIMP has been uncertain...

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Detalhes bibliográficos
Main Authors: Nosho, Katsuhiko, Kawasaki, Takako, Chan, Andrew T., Ohnishi, Mutsuko, Suemoto, Yuko, Kirkner, Gregory J., Fuchs, Charles S., Ogino, Shuji
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719983/
https://ncbi.nlm.nih.gov/pubmed/18983468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2559.2008.03161.x
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