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IGFBP3 Promoter Methylation in Colorectal Cancer: Relationship with Microsatellite Instability, CpG Island Methylator Phenotype, and p53

Insulin-like growth factor binding protein 3 (IGFBP3), which is induced by wild-type p53, regulates IGF and interacts with the TGF-β pathway. IGFBP3 promoter methylation may occur in colorectal cancer with or without the CpG island methylator phenotype (CIMP), which is associated with microsatellite...

詳細記述

保存先:
書誌詳細
主要な著者: Kawasaki, Takako, Nosho, Katsuhiko, Ohnishi, Mutsuko, Suemoto, Yuko, Kirkner, Gregory J, Fuchs, Charles S, Ogino, Shuji
フォーマット: Artigo
言語:Inglês
出版事項: Neoplasia Press Inc. 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2134905/
https://ncbi.nlm.nih.gov/pubmed/18084616
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