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18q loss of heterozygosity in microsatellite stable colorectal cancer is correlated with CpG island methylator phenotype-negative (CIMP-0) and inversely with CIMP-low and CIMP-high

BACKGROUND: The CpG island methylator phenotype (CIMP) with widespread promoter methylation is a distinct epigenetic phenotype in colorectal cancer, associated with microsatellite instability-high (MSI-high) and BRAF mutations. 18q loss of heterozygosity (LOH) commonly present in colorectal cancer w...

詳細記述

保存先:
書誌詳細
主要な著者: Ogino, Shuji, Kawasaki, Takako, Kirkner, Gregory J, Ohnishi, Mutsuko, Fuchs, Charles S
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876238/
https://ncbi.nlm.nih.gov/pubmed/17474983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-7-72
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