18q loss of heterozygosity in microsatellite stable colorectal cancer is correlated with CpG island methylator phenotype-negative (CIMP-0) and inversely with CIMP-low and CIMP-high

BACKGROUND: The CpG island methylator phenotype (CIMP) with widespread promoter methylation is a distinct epigenetic phenotype in colorectal cancer, associated with microsatellite instability-high (MSI-high) and BRAF mutations. 18q loss of heterozygosity (LOH) commonly present in colorectal cancer w...

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Detalhes bibliográficos
Main Authors: Ogino, Shuji, Kawasaki, Takako, Kirkner, Gregory J, Ohnishi, Mutsuko, Fuchs, Charles S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876238/
https://ncbi.nlm.nih.gov/pubmed/17474983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-7-72
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