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Cyclin D1 is frequently overexpressed in microsatellite unstable colorectal cancer, independent of CpG island methylator phenotype

AIMS: Cyclin D1 and cyclin-dependent kinases are commonly activated in colorectal cancer. Microsatellite instability (MSI) and CpG island methylator phenotype (CIMP) are important molecular classifiers in colorectal cancer. However, the relationship between cyclin D1, MSI and CIMP has been uncertain...

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Détails bibliographiques
Auteurs principaux: Nosho, Katsuhiko, Kawasaki, Takako, Chan, Andrew T., Ohnishi, Mutsuko, Suemoto, Yuko, Kirkner, Gregory J., Fuchs, Charles S., Ogino, Shuji
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719983/
https://ncbi.nlm.nih.gov/pubmed/18983468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2559.2008.03161.x
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