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Autotaxin Structure Activity Relationships Revealed through Lysophosphatidylcholine Analogs
Autotaxin (ATX) catalyzes the hydrolysis of lysophosphatidylcholine (LPC) to form the bioactive lipid lysophosphatidic acid (LPA). LPA stimulates cell proliferation, cell survival, and cell migration and is involved in obesity, rheumatoid arthritis, neuropathic pain, atherosclerosis and various canc...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2705928/ https://ncbi.nlm.nih.gov/pubmed/19345587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.03.030 |
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