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Autotaxin Structure Activity Relationships Revealed through Lysophosphatidylcholine Analogs
Autotaxin (ATX) catalyzes the hydrolysis of lysophosphatidylcholine (LPC) to form the bioactive lipid lysophosphatidic acid (LPA). LPA stimulates cell proliferation, cell survival, and cell migration and is involved in obesity, rheumatoid arthritis, neuropathic pain, atherosclerosis and various canc...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2705928/ https://ncbi.nlm.nih.gov/pubmed/19345587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.03.030 |
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