ST-246 Antiviral Efficacy in a Nonhuman Primate Monkeypox Model: Determination of the Minimal Effective Dose and Human Dose Justification

Therapeutics for the treatment of pathogenic orthopoxvirus infections are being sought. In the absence of patients with disease, animal models of orthopoxvirus disease are essential for evaluation of the efficacies of antiviral drugs and establishment of the appropriate dose and duration of human th...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Jordan, Robert, Goff, Arthur, Frimm, Annie, Corrado, Michael L., Hensley, Lisa E., Byrd, Chelsea M., Mucker, Eric, Shamblin, Josh, Bolken, Tove' C., Wlazlowski, Carly, Johnson, Wendy, Chapman, Jennifer, Twenhafel, Nancy, Tyavanagimatt, Shanthakumar, Amantana, Adams, Chinsangaram, Jarasvech, Hruby, Dennis E., Huggins, John
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Microbiology (ASM) 2009
الموضوعات:
Antiviral Agents
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681496/
https://ncbi.nlm.nih.gov/pubmed/19223621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01596-08
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