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Tenofovir renal toxicity targets mitochondria of renal proximal tubules
Tenofovir disoproxil fumarate (TDF) is an analog of adenosine monophosphate that inhibits HIV reverse transcriptase in HIV/AIDS. Despite its therapeutic success, renal tubular side effects are reported. The mechanisms and targets of tenofovir toxicity were determined using ‘2 × 2’ factorial protocol...
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| Principais autores: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2674517/ https://ncbi.nlm.nih.gov/pubmed/19274046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2009.14 |
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