Tenofovir Renal Proximal Tubular Toxicity Is Regulated By OAT1 and MRP4 Transporters

Tenofovir disoproxil fumarate (TDF) is an oral prodrug and acyclic nucleotide analog of adenosine monophosphate that inhibits HIV-1 (HIV) reverse transcriptase. A growing subset of TDF-treated HIV(+) individuals presented with acute renal failure, suggesting tenofovir-associated kidney-specific toxi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Kohler, James J., Hosseini, Seyed H., Green, Elgin, Abuin, Allison, Ludaway, Tomika, Russ, Rodney, Santoianni, Robert, Lewis, William
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103636/
https://ncbi.nlm.nih.gov/pubmed/21403643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2011.48
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia