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Tenofovir Renal Proximal Tubular Toxicity Is Regulated By OAT1 and MRP4 Transporters
Tenofovir disoproxil fumarate (TDF) is an oral prodrug and acyclic nucleotide analog of adenosine monophosphate that inhibits HIV-1 (HIV) reverse transcriptase. A growing subset of TDF-treated HIV(+) individuals presented with acute renal failure, suggesting tenofovir-associated kidney-specific toxi...
Tallennettuna:
| Päätekijät: | , , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2011
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3103636/ https://ncbi.nlm.nih.gov/pubmed/21403643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2011.48 |
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