In Vitro Cytotoxicity and Mitochondrial Toxicity of Tenofovir Alone and in Combination with Other Antiretrovirals in Human Renal Proximal Tubule Cells

We assessed the in vitro toxicity of tenofovir (TFV) and compared it with those of zidovudine (AZT), didanosine (ddI), ritonavir (RTV), and lopinavir (LPV) alone and in combination in human renal proximal tubule epithelial cells (RPTECs). The cells were treated with various concentrations and combin...

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Main Authors: Vidal, Francesc, Domingo, Joan Carles, Guallar, Jordi, Saumoy, Maria, Cordobilla, Begoña, Sánchez de la Rosa, Rainel, Giralt, Marta, Álvarez, Maria Luisa, López-Dupla, Miguel, Torres, Ferran, Villarroya, Francesc, Cihlar, Tomas, Domingo, Pere
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
Assuntos:
Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635212/
https://ncbi.nlm.nih.gov/pubmed/16940060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00437-06
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