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In Vitro Cytotoxicity and Mitochondrial Toxicity of Tenofovir Alone and in Combination with Other Antiretrovirals in Human Renal Proximal Tubule Cells

We assessed the in vitro toxicity of tenofovir (TFV) and compared it with those of zidovudine (AZT), didanosine (ddI), ritonavir (RTV), and lopinavir (LPV) alone and in combination in human renal proximal tubule epithelial cells (RPTECs). The cells were treated with various concentrations and combin...

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Detalhes bibliográficos
Main Authors: Vidal, Francesc, Domingo, Joan Carles, Guallar, Jordi, Saumoy, Maria, Cordobilla, Begoña, Sánchez de la Rosa, Rainel, Giralt, Marta, Álvarez, Maria Luisa, López-Dupla, Miguel, Torres, Ferran, Villarroya, Francesc, Cihlar, Tomas, Domingo, Pere
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635212/
https://ncbi.nlm.nih.gov/pubmed/16940060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00437-06
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