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Substance P stimulates human airway submucosal gland secretion mainly via a CFTR-dependent process

Chronic bacterial airway infections are the major cause of mortality in cystic fibrosis (CF). Normal airway defenses include reflex stimulation of submucosal gland mucus secretion by sensory neurons that release substance P (SubP). CFTR is an anion channel involved in fluid secretion and mutated in...

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書誌詳細
主要な著者: Choi, Jae Young, Khansaheb, Monal, Joo, Nam Soo, Krouse, Mauri E., Robbins, Robert C., Weill, David, Wine, Jeffrey J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673871/
https://ncbi.nlm.nih.gov/pubmed/19381016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI37284
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