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Synergistic airway gland mucus secretion in response to vasoactive intestinal peptide and carbachol is lost in cystic fibrosis

Cystic fibrosis (CF) is caused by dysfunction of the CF transmembrane conductance regulator (CFTR), an anion channel whose dysfunction leads to chronic bacterial and fungal airway infections via a pathophysiological cascade that is incompletely understood. Airway glands, which produce most airway mu...

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Detalhes bibliográficos
Main Authors: Choi, Jae Young, Joo, Nam Soo, Krouse, Mauri E., Wu, Jin V., Robbins, Robert C., Ianowski, Juan P., Hanrahan, John W., Wine, Jeffrey J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1974867/
https://ncbi.nlm.nih.gov/pubmed/17853942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31992
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