Synergistic airway gland mucus secretion in response to vasoactive intestinal peptide and carbachol is lost in cystic fibrosis

Cystic fibrosis (CF) is caused by dysfunction of the CF transmembrane conductance regulator (CFTR), an anion channel whose dysfunction leads to chronic bacterial and fungal airway infections via a pathophysiological cascade that is incompletely understood. Airway glands, which produce most airway mu...

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Autors principals: Choi, Jae Young, Joo, Nam Soo, Krouse, Mauri E., Wu, Jin V., Robbins, Robert C., Ianowski, Juan P., Hanrahan, John W., Wine, Jeffrey J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2007
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1974867/
https://ncbi.nlm.nih.gov/pubmed/17853942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31992
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