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Defective Fluid Secretion from Submucosal Glands of Nasal Turbinates from CFTR(-/-) and CFTR(ΔF508/ΔF508) Pigs

BACKGROUND: Cystic fibrosis (CF), caused by reduced CFTR function, includes severe sinonasal disease which may predispose to lung disease. Newly developed CF pigs provide models to study the onset of CF pathophysiology. We asked if glands from pig nasal turbinates have secretory responses similar to...

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Detalhes bibliográficos
Main Authors: Cho, Hyung-Ju, Joo, Nam Soo, Wine, Jeffrey J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164206/
https://ncbi.nlm.nih.gov/pubmed/21935358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024424
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