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Endogenous surface expression of ΔF508 CFTR mediates cAMP-stimulated Cl(−) current in CFTR (ΔF508/ΔF508) pig thyroid epithelial cells
The Cystic Fibrosis Transmembrane Conductance Regulator, CFTR, is both an anion channel and a regulator of other transport proteins. CFTR gene mutations underlie the human disease, Cystic Fibrosis (CF). The most common CFTR mutation, ΔF508, produces a misfolded protein which traffics improperly. The...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3253219/ https://ncbi.nlm.nih.gov/pubmed/21948195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/expphysiol.2011.060756 |
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