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Altered ion transport by thyroid epithelia from CFTR(−/−) pigs suggests mechanisms for hypothyroidism in Cystic Fibrosis
Subclinical hypothyroidism has been linked to Cystic Fibrosis (CF), and the cystic fibrosis transmembrane conductance regulator (CFTR) shown to be expressed in the thyroid. The thyroid epithelium secretes Cl(−) and absorbs Na(+) in response to cAMP. Chloride secretion may provide a counter-ion for t...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2991370/ https://ncbi.nlm.nih.gov/pubmed/20729267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/expphysiol.2010.054700 |
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