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Hyposecretion of fluid from tracheal submucosal glands of CFTR-deficient pigs
Cystic fibrosis (CF) results from mutations that disrupt CF transmembrane conductance regulator (CFTR), an anion channel found mainly in apical membranes of epithelial cells. CF leads to chronic infection of the airways with normally innocuous bacteria and fungi. Hypotheses to explain the pathophysi...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2929738/ https://ncbi.nlm.nih.gov/pubmed/20739758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43466 |
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