Substance P stimulates human airway submucosal gland secretion mainly via a CFTR-dependent process

Chronic bacterial airway infections are the major cause of mortality in cystic fibrosis (CF). Normal airway defenses include reflex stimulation of submucosal gland mucus secretion by sensory neurons that release substance P (SubP). CFTR is an anion channel involved in fluid secretion and mutated in...

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Detalles Bibliográficos
Main Authors: Choi, Jae Young, Khansaheb, Monal, Joo, Nam Soo, Krouse, Mauri E., Robbins, Robert C., Weill, David, Wine, Jeffrey J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673871/
https://ncbi.nlm.nih.gov/pubmed/19381016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI37284
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