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Substance P stimulates human airway submucosal gland secretion mainly via a CFTR-dependent process
Chronic bacterial airway infections are the major cause of mortality in cystic fibrosis (CF). Normal airway defenses include reflex stimulation of submucosal gland mucus secretion by sensory neurons that release substance P (SubP). CFTR is an anion channel involved in fluid secretion and mutated in...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2673871/ https://ncbi.nlm.nih.gov/pubmed/19381016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI37284 |
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