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Age-Dependent Alterations of Corticostriatal Activity in the YAC128 Mouse Model of Huntington Disease

Huntington disease is a genetic neurodegenerative disorder that produces motor, neuropsychiatric, and cognitive deficits and is caused by an abnormal expansion of the CAG tract in the huntingtin (htt) gene. In humans, mutated htt induces a preferential loss of medium spiny neurons in the striatum an...

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Bibliografiset tiedot
Päätekijät: Joshi, Prasad R., Wu, Nan-Ping, André, Véronique M., Cummings, Damian M., Cepeda, Carlos, Joyce, John A., Carroll, Jeffrey B., Leavitt, Blair R., Hayden, Michael R., Levine, Michael S., Bamford, Nigel S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670193/
https://ncbi.nlm.nih.gov/pubmed/19244517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5687-08.2009
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