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Age-Dependent Alterations of Corticostriatal Activity in the YAC128 Mouse Model of Huntington Disease
Huntington disease is a genetic neurodegenerative disorder that produces motor, neuropsychiatric, and cognitive deficits and is caused by an abnormal expansion of the CAG tract in the huntingtin (htt) gene. In humans, mutated htt induces a preferential loss of medium spiny neurons in the striatum an...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Society for Neuroscience
2009
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2670193/ https://ncbi.nlm.nih.gov/pubmed/19244517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5687-08.2009 |
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