Age-Dependent Alterations of Corticostriatal Activity in the YAC128 Mouse Model of Huntington Disease

Huntington disease is a genetic neurodegenerative disorder that produces motor, neuropsychiatric, and cognitive deficits and is caused by an abnormal expansion of the CAG tract in the huntingtin (htt) gene. In humans, mutated htt induces a preferential loss of medium spiny neurons in the striatum an...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Joshi, Prasad R., Wu, Nan-Ping, André, Véronique M., Cummings, Damian M., Cepeda, Carlos, Joyce, John A., Carroll, Jeffrey B., Leavitt, Blair R., Hayden, Michael R., Levine, Michael S., Bamford, Nigel S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2009
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670193/
https://ncbi.nlm.nih.gov/pubmed/19244517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5687-08.2009
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