Age-Dependent Alterations of Corticostriatal Activity in the YAC128 Mouse Model of Huntington Disease

Huntington disease is a genetic neurodegenerative disorder that produces motor, neuropsychiatric, and cognitive deficits and is caused by an abnormal expansion of the CAG tract in the huntingtin (htt) gene. In humans, mutated htt induces a preferential loss of medium spiny neurons in the striatum an...

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Detalhes bibliográficos
Main Authors: Joshi, Prasad R., Wu, Nan-Ping, André, Véronique M., Cummings, Damian M., Cepeda, Carlos, Joyce, John A., Carroll, Jeffrey B., Leavitt, Blair R., Hayden, Michael R., Levine, Michael S., Bamford, Nigel S.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670193/
https://ncbi.nlm.nih.gov/pubmed/19244517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5687-08.2009
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