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Identifying and Characterizing a Functional HIV-1 Reverse Transcriptase-binding Site on Integrase
Integrase (IN) from human immunodeficiency virus, type 1 (HIV-1) exerts pleiotropic effects in the viral replication cycle. Besides integration, IN mutations can impact nuclear import, viral maturation, and reverse transcription. IN and reverse transcriptase (RT) interact in vitro, and the IN C-term...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2658086/ https://ncbi.nlm.nih.gov/pubmed/19150986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806241200 |
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