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Coevolutionary Analysis Identifies Protein–Protein Interaction Sites between HIV-1 Reverse Transcriptase and Integrase

The replication of human immunodeficiency virus-1 (HIV-1) requires reverse transcription of the viral RNA genome and integration of newly synthesized pro-viral DNA into the host genome. This is mediated by the viral proteins reverse transcriptase (RT) and integrase (IN). The formation and stabilizat...

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Detalhes bibliográficos
Publicado no:Virus Evol
Main Authors: Hetti Arachchilage, Madara, Piontkivska, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854294/
https://ncbi.nlm.nih.gov/pubmed/27152230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ve/vew002
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