Interaction between Reverse Transcriptase and Integrase Is Required for Reverse Transcription during HIV-1 Replication

Human immunodeficiency virus type 1 (HIV-1) replication requires reverse transcription of its RNA genome into a double-stranded cDNA copy, which is then integrated into the host cell chromosome. The essential steps of reverse transcription and integration are catalyzed by the viral enzymes reverse t...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Tekeste, Shewit S., Wilkinson, Thomas A., Weiner, Ethan M., Xu, Xiaowen, Miller, Jennifer T., Le Grice, Stuart F. J., Clubb, Robert T., Chow, Samson A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645309/
https://ncbi.nlm.nih.gov/pubmed/26401032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01471-15
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