Molecular Mechanisms by Which Human Immunodeficiency Virus Type 1 Integrase Stimulates the Early Steps of Reverse Transcription

Reverse transcriptase (RT) and integrase (IN) are two essential enzymes that play a critical role in synthesis and integration of the retroviral cDNA, respectively. For human immunodeficiency virus type 1 (HIV-1), RT and IN physically interact and certain mutations and deletions of IN result in viru...

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Hlavní autoři: Dobard, Charles W., Briones, Marisa S., Chow, Samson A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045400/
https://ncbi.nlm.nih.gov/pubmed/17626089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00519-07
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