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Requirement for Integrase during Reverse Transcription of Human Immunodeficiency Virus Type 1 and the Effect of Cysteine Mutations of Integrase on Its Interactions with Reverse Transcriptase

Retroviral integrase catalyzes the essential step of integrating a double-stranded DNA copy of the viral genome into a host cell chromosome. Mutational studies have revealed that integrase is involved in additional steps of viral replication, but the mechanism for the pleiotropic effect is not well...

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Bibliografski detalji
Glavni autori: Zhu, Kai, Dobard, Charles, Chow, Samson A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC400327/
https://ncbi.nlm.nih.gov/pubmed/15113886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.10.5045-5055.2004
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