Identifying and Characterizing a Functional HIV-1 Reverse Transcriptase-binding Site on Integrase

Integrase (IN) from human immunodeficiency virus, type 1 (HIV-1) exerts pleiotropic effects in the viral replication cycle. Besides integration, IN mutations can impact nuclear import, viral maturation, and reverse transcription. IN and reverse transcriptase (RT) interact in vitro, and the IN C-term...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wilkinson, Thomas A., Januszyk, Kurt, Phillips, Martin L., Tekeste, Shewit S., Zhang, Min, Miller, Jennifer T., Le Grice, Stuart F. J., Clubb, Robert T., Chow, Samson A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2009
Gaiak:
Enzyme Catalysis and Regulation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658086/
https://ncbi.nlm.nih.gov/pubmed/19150986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806241200
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