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Identifying and Characterizing a Functional HIV-1 Reverse Transcriptase-binding Site on Integrase

Integrase (IN) from human immunodeficiency virus, type 1 (HIV-1) exerts pleiotropic effects in the viral replication cycle. Besides integration, IN mutations can impact nuclear import, viral maturation, and reverse transcription. IN and reverse transcriptase (RT) interact in vitro, and the IN C-term...

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書誌詳細
主要な著者: Wilkinson, Thomas A., Januszyk, Kurt, Phillips, Martin L., Tekeste, Shewit S., Zhang, Min, Miller, Jennifer T., Le Grice, Stuart F. J., Clubb, Robert T., Chow, Samson A.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658086/
https://ncbi.nlm.nih.gov/pubmed/19150986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806241200
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