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Luciferase Fragment Complementation Imaging of Conformational Changes in the Epidermal Growth Factor Receptor

Crystal structures of the epidermal growth factor (EGF) receptor suggest that its activation is associated with extensive conformational changes in both the extracellular and intracellular domains. However, evidence of these structural dynamics in intact cells has been lacking. Here we use luciferas...

詳細記述

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書誌詳細
主要な著者: Yang, Katherine S., Ilagan, Ma. Xenia G., Piwnica-Worms, David, Pike, Linda J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658043/
https://ncbi.nlm.nih.gov/pubmed/19171934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808041200
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