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Luciferase Fragment Complementation Imaging of Conformational Changes in the Epidermal Growth Factor Receptor
Crystal structures of the epidermal growth factor (EGF) receptor suggest that its activation is associated with extensive conformational changes in both the extracellular and intracellular domains. However, evidence of these structural dynamics in intact cells has been lacking. Here we use luciferas...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2658043/ https://ncbi.nlm.nih.gov/pubmed/19171934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808041200 |
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