Chargement en cours...
Mechanics of EGF Receptor/ErbB2 kinase activation revealed by luciferase fragment complementation imaging
Binding of EGF to its receptor induces dimerization of the normally monomeric receptor. Activation of its intracellular tyrosine kinase then occurs through the formation of an asymmetric kinase dimer in which one subunit, termed the “receiver” kinase, is activated by interaction with the other subun...
Enregistré dans:
| Auteurs principaux: | , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2012
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3252912/ https://ncbi.nlm.nih.gov/pubmed/22190492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111316109 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|