Načítá se...

Mechanics of EGF Receptor/ErbB2 kinase activation revealed by luciferase fragment complementation imaging

Binding of EGF to its receptor induces dimerization of the normally monomeric receptor. Activation of its intracellular tyrosine kinase then occurs through the formation of an asymmetric kinase dimer in which one subunit, termed the “receiver” kinase, is activated by interaction with the other subun...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Macdonald-Obermann, Jennifer L., Piwnica-Worms, David, Pike, Linda J.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252912/
https://ncbi.nlm.nih.gov/pubmed/22190492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111316109
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!