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Real-time imaging of Notch activation using a Luciferase Complementation-based Reporter
Notch signaling regulates many cellular processes during development and adult tissue renewal. Upon ligand binding, Notch receptors undergo ectodomain shedding followed by γ-secretase-mediated release of the Notch intracellular domain (NICD), which translocates to the nucleus and associates with the...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3387985/ https://ncbi.nlm.nih.gov/pubmed/21775282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2001656 |
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