Quantitative Dissection of the Notch:CSL Interaction: Insights into the Notch Transcriptional Switch

Complex formation between the intracellular domain of the Notch receptor (NICD) and the transcription factor CSL is indispensable for transcriptional activation. To understand how NICD displaces CSL-associated co-repressors, we have quantified the binding of different Notch1 ICD regions to a key int...

Full description

Saved in:
Bibliographic Details
Main Authors: Lubman, Olga Y., Ilagan, Ma. Xenia G., Kopan, Raphael, Barrick, Doug
Format: Artigo
Language:Inglês
Published: 2006
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851696/
https://ncbi.nlm.nih.gov/pubmed/17070841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.09.071
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items