Quantitative Dissection of the Notch:CSL Interaction: Insights into the Notch Transcriptional Switch

Complex formation between the intracellular domain of the Notch receptor (NICD) and the transcription factor CSL is indispensable for transcriptional activation. To understand how NICD displaces CSL-associated co-repressors, we have quantified the binding of different Notch1 ICD regions to a key int...

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Hlavní autoři: Lubman, Olga Y., Ilagan, Ma. Xenia G., Kopan, Raphael, Barrick, Doug
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851696/
https://ncbi.nlm.nih.gov/pubmed/17070841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.09.071
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