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Quantitative Dissection of the Notch:CSL Interaction: Insights into the Notch Transcriptional Switch

Complex formation between the intracellular domain of the Notch receptor (NICD) and the transcription factor CSL is indispensable for transcriptional activation. To understand how NICD displaces CSL-associated co-repressors, we have quantified the binding of different Notch1 ICD regions to a key int...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Lubman, Olga Y., Ilagan, Ma. Xenia G., Kopan, Raphael, Barrick, Doug
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851696/
https://ncbi.nlm.nih.gov/pubmed/17070841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.09.071
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