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Quantitative Dissection of the Notch:CSL Interaction: Insights into the Notch Transcriptional Switch
Complex formation between the intracellular domain of the Notch receptor (NICD) and the transcription factor CSL is indispensable for transcriptional activation. To understand how NICD displaces CSL-associated co-repressors, we have quantified the binding of different Notch1 ICD regions to a key int...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1851696/ https://ncbi.nlm.nih.gov/pubmed/17070841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.09.071 |
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