Reassessment of the Role of Mut S Homolog 5 in Ig Class Switch Recombination Shows Lack of Involvement in cis- and trans-Switching

When B cells are activated after immunization or infection, they exchange the gene encoding the Ig H chain C region by class switch recombination (CSR). CSR generally occurs by an intrachromosomal deletional recombination within switch (S) region sequences. However, ∼10% of CSR events occur between...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Guikema, Jeroen E. J., Schrader, Carol E., Leus, Niek G. J., Ucher, Anna, Linehan, Erin K., Werling, Uwe, Edelmann, Winfried, Stavnezer, Janet
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656362/
https://ncbi.nlm.nih.gov/pubmed/19050263
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker