Reduced Isotype Switching in Splenic B Cells from Mice Deficient in Mismatch Repair Enzymes

Mice deficient in various mismatch repair (MMR) enzymes were examined to determine whether this repair pathway is involved in antibody class switch recombination. Splenic B cells from mice deficient in Msh2, Mlh1, Pms2, or Mlh1 and Pms2 were stimulated in culture with lipopolysaccharide (LPS) to ind...

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Hlavní autoři: Schrader, Carol E., Edelmann, Winfried, Kucherlapati, Raju, Stavnezer, Janet
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1999
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195591/
https://ncbi.nlm.nih.gov/pubmed/10430621
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