Formation and Stability of a Vinyl Carbanion at the Active Site of Orotidine 5′-Monophosphate Decarboxylase: pK(a) of the C-6 Proton of Enzyme-Bound UMP

Lignende værker

• Product Deuterium Isotope Effects for Orotidine 5'-Monophosphate Decarboxylase: Effect of Changing Substrate and Enzyme Structure on the Partitioning of the Vinyl Carbanion Reaction Intermediate
  af: Toth, Krisztina, et al.
  Udgivet: (2010)
• Product Deuterium Isotope Effect for Orotidine 5'-Monophosphate Decarboxylase: Evidence for the Existence of a Short-Lived Carbanion Intermediate
  af: Toth, Krisztina, et al.
  Udgivet: (2007)
• Proton Transfer from C-6 of Uridine 5′-Monophosphate Catalyzed by Orotidine 5′-Monophosphate Decarboxylase: Formation and Stability of a Vinyl Carbanion Intermediate and the Effect of a 5-Fluoro Substituent
  af: Tsang, Wing-Yin, et al.
  Udgivet: (2012)
• Role of a Guanidinium Cation-Phosphodianion Pair in Stabilizing the Vinyl Carbanion Intermediate of Orotidine 5'-Phosphate Decarboxylase-Catalyzed Reactions.()
  af: Goryanova, Bogdana, et al.
  Udgivet: (2013)
• Mechanism of the Orotidine 5’-Monophosphate Decarboxylase-Catalyzed Reaction: Effect of Solvent Viscosity on Kinetic Constants
  af: Wood, B. McKay, et al.
  Udgivet: (2009)