Utilization of l-Ascorbate by Escherichia coli K-12: Assignments of Functions to Products of the yjf-sga and yia-sgb Operons

Por Yew, Wen Shan, Gerlt, John A.
Publicado em 2002

Can sequence determine function?

Por Gerlt, John A, Babbitt, Patricia C
Publicado em 2000

Enzyme (Re)Design: Lessons from Natural Evolution and Computation

Por Gerlt, John A., Babbitt, Patricia C.
Publicado em 2009

OMP Decarboxylase: Phosphodianion Binding Energy is Used to Stabilize a Vinyl Carbanion Intermediate

Por Goryanova, Bogdana, Amyes, Tina L., Gerlt, John A., Richard, John P.
Publicado em 2011

Purification, crystallization and structural elucidation of d-galactaro-1,4-lactone cycloisomerase from Agrobacterium tumefaciens involved in pectin degradation

Por Vetting, Matthew W., Bouvier, Jason T., Gerlt, John A., Almo, Steven C.
Publicado no Acta Crystallogr F Struct Biol Commun (2016)

A gold standard set of mechanistically diverse enzyme superfamilies

Por Brown, Shoshana D, Gerlt, John A, Seffernick, Jennifer L, Babbitt, Patricia C
Publicado em 2006

Divergent Evolution in Enolase Superfamily: Strategies for Assigning Functions

Por Gerlt, John A., Babbitt, Patricia C., Jacobson, Matthew P., Almo, Steven C.
Publicado em 2012

Mechanistic Diversity in the RuBisCO Superfamily: A Novel Isomerization Reaction Catalyzed by the RuBisCO-Like Protein from Rhodospirillum rubrum

Por Imker, Heidi J., Singh, Jaya, Warlick, Benjamin P., Tabita, F. Robert, Gerlt, John A.
Publicado em 2008

Formation and Stability of a Vinyl Carbanion at the Active Site of Orotidine 5′-Monophosphate Decarboxylase: pK(a) of the C-6 Proton of Enzyme-Bound UMP

Por Amyes, Tina L., Wood, Bryant M., Chan, Kui, Gerlt, John A., Richard, John P.
Publicado em 2008

Role of a Guanidinium Cation-Phosphodianion Pair in Stabilizing the Vinyl Carbanion Intermediate of Orotidine 5'-Phosphate Decarboxylase-Catalyzed Reactions.()

Por Goryanova, Bogdana, Goldman, Lawrence M., Amyes, Tina L., Gerlt, John A, Richard, John P.
Publicado em 2013

Galactaro δ-Lactone Isomerase: Lactone Isomerization by a Member of the Amidohydrolase Superfamily

Por Bouvier, Jason T., Groninger-Poe, Fiona P., Vetting, Matthew, Almo, Steven C., Gerlt, John A.
Publicado em 2014

Enzyme Architecture: Deconstruction of the Enzyme-Activating Phosphodianion Interactions of Orotidine 5′-Monophosphate Decarboxylase

Por Goldman, Lawrence M., Amyes, Tina L., Goryanova, Bogdana, Gerlt, John A., Richard, John P.
Publicado no J Am Chem Soc (2014)

Structural Basis for Substrate Specificity in Phosphate Binding (β/α)(8)-Barrels: D-Allulose 6-Phosphate 3-Epimerase from Escherichia coli K-12

Por Chan, Kui K., Fedorov, Alexander A., Fedorov, Elena V., Almo, Steven C., Gerlt, John A.
Publicado em 2008

Dissecting the Total Transition State Stabilization Provided by Amino Acid Side-Chains at Orotidine 5′-Monophosphate Decarboxylase: A Two-Part Substrate Approach

Por Barnett, Shonoi A., Amyes, Tina L., Wood, Bryant M., Gerlt, John A., Richard, John P.
Publicado em 2008

Mechanistic Diversity in the RuBisCO Superfamily: RuBisCO from Rhodospirillum rubrum is Not Promiscuous for Reactions Catalyzed by RuBisCO-Like Proteins (RLPs)()

Por Warlick, Benjamin P. E., Imker, Heidi J., Sriram, Jaya, Tabita, F. Robert, Gerlt, John A.
Publicado em 2012

Identification of the in Vivo Function of the High-Efficiency d-Mannonate Dehydratase in Caulobacter crescentus NA1000 from the Enolase Superfamily

Por Wichelecki, Daniel J., Graff, Dylan C., Al-Obaidi, Nawar, Almo, Steven C., Gerlt, John A.
Publicado em 2014

Product Deuterium Isotope Effect for Orotidine 5'-Monophosphate Decarboxylase: Evidence for the Existence of a Short-Lived Carbanion Intermediate

Por Toth, Krisztina, Amyes, Tina L., Wood, Bryant M., Chan, Kui, Gerlt, John A., Richard, John P.
Publicado em 2007

Mechanism of the Orotidine 5’-Monophosphate Decarboxylase-Catalyzed Reaction: Effect of Solvent Viscosity on Kinetic Constants

Por Wood, B. McKay, Chan, Kui K., Amyes, Tina L., Richard, John P., Gerlt, John A.
Publicado em 2009

Activation of R235A Mutant Orotidine 5'-Monophosphate Decarboxylase by the Guanidinium Cation: Effective Molarity of the Cationic Side Chain of Arg-235

Por Barnett, Shonoi A., Amyes, Tina L., Wood, B. McKay, Gerlt, John A., Richard, John P.
Publicado em 2010

Product Deuterium Isotope Effects for Orotidine 5'-Monophosphate Decarboxylase: Effect of Changing Substrate and Enzyme Structure on the Partitioning of the Vinyl Carbanion Reactio...

Por Toth, Krisztina, Amyes, Tina L., Wood, Bryant M., Chan, Kui, Gerlt, John A., Richard, John P.
Publicado em 2010