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Mechanism of the Orotidine 5’-Monophosphate Decarboxylase-Catalyzed Reaction: Effect of Solvent Viscosity on Kinetic Constants
Orotidine 5’-monophosphate decarboxylase (OMPDC) is an exceptionally proficient catalyst: the rate acceleration (k(cat)/k(non)) is 7.1 × 10(16) and the proficiency [(k(cat)/K(M))/k(non)] is 4.8 × 10(22) M(−1). The structural basis for the large rate acceleration and proficiency is unknown, although...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2735758/ https://ncbi.nlm.nih.gov/pubmed/19435313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9006226 |
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