Reengineering the glutathione S-transferase scaffold: A rational design strategy pays off

Por Babbitt, Patricia C.
Publicado em 2000

New computational approaches to understanding molecular protein function

Por Fetrow, Jacquelyn S., Babbitt, Patricia C.
Publicado no PLoS Comput Biol (2018)

Can sequence determine function?

Por Gerlt, John A, Babbitt, Patricia C
Publicado em 2000

Enzyme (Re)Design: Lessons from Natural Evolution and Computation

Por Gerlt, John A., Babbitt, Patricia C.
Publicado em 2009

Glutathione Transferases Are Structural and Functional Outliers in the Thioredoxin Fold

Por Atkinson, Holly J., Babbitt, Patricia C.
Publicado em 2009

An Atlas of the Thioredoxin Fold Class Reveals the Complexity of Function-Enabling Adaptations

Por Atkinson, Holly J., Babbitt, Patricia C.
Publicado em 2009

Inference of Functional Properties from Large-scale Analysis of Enzyme Superfamilies

Por Brown, Shoshana D., Babbitt, Patricia C.
Publicado em 2012

Pythoscape: a framework for generation of large protein similarity networks

Por Barber, Alan E., Babbitt, Patricia C.
Publicado em 2012

Topological Variation in the Evolution of New Reactions in Functionally Diverse Enzyme Superfamilies

Por Meng, Elaine C., Babbitt, Patricia C.
Publicado em 2011

Towards mechanistic classification of enzyme functions

Por Almonacid, Daniel E., Babbitt, Patricia C.
Publicado em 2011

New Insights about Enzyme Evolution from Large Scale Studies of Sequence and Structure Relationships

Por Brown, Shoshana D., Babbitt, Patricia C.
Publicado em 2014

Effusion: prediction of protein function from sequence similarity networks

Por Yunes, Jeffrey M, Babbitt, Patricia C
Publicado no Bioinformatics (2019)

Evolution of Function in the “Two Dinucleotide Binding Domains” Flavoproteins

Por Ojha, Sunil, Meng, Elaine C, Babbitt, Patricia C
Publicado em 2007

Evolutionarily Conserved Substrate Substructures for Automated Annotation of Enzyme Superfamilies

Por Chiang, Ranyee A., Sali, Andrej, Babbitt, Patricia C.
Publicado em 2008

The global cysteine peptidase landscape in parasites

Por Atkinson, Holly J, Babbitt, Patricia C, Sajid, Mohammed
Publicado em 2009

A semiautomated approach to gene discovery through expressed sequence tag data mining: Discovery of new human transporter genes

Por Brown, Shoshana, Chang, Jean l., Sadee, Wolfgang, Babbitt, Patricia C.
Publicado em 2003

Evolutionary and molecular foundations of multiple contemporary functions of the nitroreductase superfamily

Por Akiva, Eyal, Copp, Janine N., Tokuriki, Nobuhiko, Babbitt, Patricia C.
Publicado no Proc Natl Acad Sci U S A (2017)

Evaluating Functional Annotations of Enzymes Using the Gene Ontology

Por Holliday, Gemma L., Davidson, Rebecca, Akiva, Eyal, Babbitt, Patricia C.
Publicado no Methods Mol Biol (2017)

Annotation Error in Public Databases: Misannotation of Molecular Function in Enzyme Superfamilies

Por Schnoes, Alexandra M., Brown, Shoshana D., Dodevski, Igor, Babbitt, Patricia C.
Publicado em 2009

Improving the quality of protein similarity network clustering algorithms using the network edge weight distribution

Por Apeltsin, Leonard, Morris, John H., Babbitt, Patricia C., Ferrin, Thomas E.
Publicado em 2011