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New Insights about Enzyme Evolution from Large Scale Studies of Sequence and Structure Relationships

Understanding how enzymes have evolved offers clues about their structure-function relationships and mechanisms. Here, we describe evolution of functionally diverse enzyme superfamilies, each representing a large set of sequences that evolved from a common ancestor and that retain conserved features...

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Detalhes bibliográficos
Main Authors: Brown, Shoshana D., Babbitt, Patricia C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215206/
https://ncbi.nlm.nih.gov/pubmed/25210038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R114.569350
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