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Evolutionarily Conserved Substrate Substructures for Automated Annotation of Enzyme Superfamilies

The evolution of enzymes affects how well a species can adapt to new environmental conditions. During enzyme evolution, certain aspects of molecular function are conserved while other aspects can vary. Aspects of function that are more difficult to change or that need to be reused in multiple contex...

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Detalhes bibliográficos
Main Authors: Chiang, Ranyee A., Sali, Andrej, Babbitt, Patricia C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453236/
https://ncbi.nlm.nih.gov/pubmed/18670595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000142
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