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Evolutionarily Conserved Substrate Substructures for Automated Annotation of Enzyme Superfamilies

The evolution of enzymes affects how well a species can adapt to new environmental conditions. During enzyme evolution, certain aspects of molecular function are conserved while other aspects can vary. Aspects of function that are more difficult to change or that need to be reused in multiple contex...

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Hlavní autoři: Chiang, Ranyee A., Sali, Andrej, Babbitt, Patricia C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453236/
https://ncbi.nlm.nih.gov/pubmed/18670595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000142
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