A carregar...

Proton Transfer from C-6 of Uridine 5′-Monophosphate Catalyzed by Orotidine 5′-Monophosphate Decarboxylase: Formation and Stability of a Vinyl Carbanion Intermediate and the Effect of a 5-Fluoro Substituent

The exchange for deuterium of the C-6 protons of uridine 5′-monophosphate (UMP) and 5-fluorouridine 5′-monophosphate (F-UMP) catalyzed by yeast orotidine 5′-monophosphate decarboxylase (ScOMPDC) at pD 6.5 – 9.3 and 25 °C was monitored by (1)H NMR spectroscopy. Deuterium exchange proceeds by proton t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Tsang, Wing-Yin, Wood, B. McKay, Wong, Freeman M., Wu, Weiming, Gerlt, John A., Amyes, Tina L., Richard, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434256/
https://ncbi.nlm.nih.gov/pubmed/22812629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3058474
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!