Chargement en cours...

Cyclophilin A Levels Dictate Infection Efficiency of Human Immunodeficiency Virus Type 1 Capsid Escape Mutants A92E and G94D

Cyclophilin A (CypA) is an important human immunodeficiency virus type 1 (HIV-1) cofactor in human cells. HIV-1 A92E and G94D capsid escape mutants arise during CypA inhibition and in certain cell lines are dependent on CypA inhibition. Here we show that dependence on CypA inhibition is due to high...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ylinen, Laura M. J., Schaller, Torsten, Price, Amanda, Fletcher, Adam J., Noursadeghi, Mahdad, James, Leo C., Towers, Greg J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643744/
https://ncbi.nlm.nih.gov/pubmed/19073742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01876-08
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!