HIV-1 capsid undergoes coupled binding and isomerization by the nuclear pore protein NUP358

BACKGROUND: Lentiviruses such as HIV-1 can be distinguished from other retroviruses by the cyclophilin A-binding loop in their capsid and their ability to infect non-dividing cells. Infection of non-dividing cells requires transport through the nuclear pore but how this is mediated is unknown. RESUL...

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Main Authors: Bichel, Katsiaryna, Price, Amanda J, Schaller, Torsten, Towers, Greg J, Freund, Stefan MV, James, Leo C
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750474/
https://ncbi.nlm.nih.gov/pubmed/23902822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-81
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