Loss of Caveolin-3 Induces a Lactogenic Microenvironment that Is Protective Against Mammary Tumor Formation

Here, we show that functional loss of a single gene is sufficient to confer constitutive milk protein production and protection against mammary tumor formation. Caveolin-3 (Cav-3), a muscle-specific caveolin-related gene, is highly expressed in muscle cells. We demonstrate that Cav-3 is also express...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Sotgia, Federica, Casimiro, Mathew C., Bonuccelli, Gloria, Liu, Manran, Whitaker-Menezes, Diana, Er, Ozlem, Daumer, Kristin M., Mercier, Isabelle, Witkiewicz, Agnieszka K., Minetti, Carlo, Capozza, Franco, Gormley, Michael, Quong, Andrew A., Rui, Hallgeir, Frank, Philippe G., Milliman, Janet N., Knudsen, Erik S., Zhou, Jie, Wang, Chenguang, Pestell, Richard G., Lisanti, Michael P.
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Investigative Pathology 2009
الموضوعات:
Regular Articles
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630569/
https://ncbi.nlm.nih.gov/pubmed/19164602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080653
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