Loss of Caveolin-3 Induces a Lactogenic Microenvironment that Is Protective Against Mammary Tumor Formation

Here, we show that functional loss of a single gene is sufficient to confer constitutive milk protein production and protection against mammary tumor formation. Caveolin-3 (Cav-3), a muscle-specific caveolin-related gene, is highly expressed in muscle cells. We demonstrate that Cav-3 is also express...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Sotgia, Federica, Casimiro, Mathew C., Bonuccelli, Gloria, Liu, Manran, Whitaker-Menezes, Diana, Er, Ozlem, Daumer, Kristin M., Mercier, Isabelle, Witkiewicz, Agnieszka K., Minetti, Carlo, Capozza, Franco, Gormley, Michael, Quong, Andrew A., Rui, Hallgeir, Frank, Philippe G., Milliman, Janet N., Knudsen, Erik S., Zhou, Jie, Wang, Chenguang, Pestell, Richard G., Lisanti, Michael P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2009
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630569/
https://ncbi.nlm.nih.gov/pubmed/19164602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080653
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky